International Journal of Scientific Research and Engineering Development

International Journal of Scientific Research and Engineering Development

( International Peer Reviewed Open Access Journal ) ISSN [ Online ] : 2581 - 7175

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Biota Screening of Potent Isolates of Antibiotic Producing Staphylococcus Species from Marine Sediment

    International Journal of Scientific Research and Engineering Development (IJSRED)

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Published Issue : Volume-3 Issue-6
Year of Publication : 2020
Unique Identification Number : IJSRED-V3I6P37
Authors : Tirupathi Rao A, Srinivas N, Radha Krishna E, Veerendra Kumar B
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Abstract :

Microorganisms play critical role in human health and its functions colonizes in the human body and maintain consistent health as well. Protein based antibiotics play a pivotal role in curing the human diseases. Current research aimed to discover, screen and isolate the peptide based antibiotics producing Staphylococci from Visakhapatnam coastal area. Isolate(s) screened were identified as Staphylococcus species and subjected for further screening to discover a bacterium with an efficient antibiotic producing activity. 129 strain(s) out of 260 were isolated from marine sediment are Staphylococcus species. Eighty-five isolates of marine sediment bacteria were isolated using nutrient agar medium. Among 85 isolates, six exhibited antimicrobial activities against human pathogens such as Escherichia coli MTCC443, Pseudomonas aeruginosa MTCC424, Proteus vulgaris MTCC1771, Bacillus cereus MTCC430, Bacillus subtilis MTCC441 and Staphylococcus aureus MTCC3160. Resulting mean diameter of inhibitory zones (19 mm) revealed isolate (Staphylococcus epidermidis) was the most potent among all the isolates. The current investigation revealed that the diversity and antimicrobial activity have increased the scope of finding industrially important marine bacteria from the coast of Visakhapatnam and these organisms could be vital sources for the discovery of industrially useful bioactive molecules.